Research Leader - RNA Biology - Find My Rizq
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Charles River Laboratories

For 70 years, Charles River workers have labored collectively to help within the discovery, improvement and secure manufacture of latest drug therapies. When you be part of our household, you’ll have a major influence on the well being and well-being of individuals throughout the globe. Whether your background is in life sciences, finance, IT, gross sales or one other space, your abilities will play an vital function within the work we carry out. In return, we’ll provide help to construct a profession that you may really feel captivated with.Job AbstractCharles River have an thrilling alternative for a self-motivated Senior Scientist / Research Leader to affix our laboratories in Chesterford Research Park, Saffron Walden. This is a senior scientific function which might be predominantly lab based mostly, offering the chance so that you can drive ahead and innovate the realm of RNA biology.  You could have a broad understanding of scientific and technical requirements, assay ideas, ideas and strategies gained by expertise in Hit Identification screening and broader drug-discovery. A specific background in making use of innovative molecular biology strategies to focus on validation along with expertise of creating and performing RNA detection assays (ideally exploiting multi-parametric end-points) is fascinating. Within this function, you’ll be a part of a cross-functional crew of scientists working on the forefront of drug discovery, collaborating and influencing different teams throughout the organisation together with computational chemistry, medicinal chemistry and DMPK. You might be engaged on a variety of targets and modalities, in an effort to remedy complicated issues, interpret and report knowledge to advance drug discovery initiatives for our shoppers. This difficult and dynamic atmosphere will present the perfect alternative to showcase your experience, develop your profession and contribute on to the invention of latest medicines. Our very best candidate could have a level or PhD stage qualification and a number of other years’ confirmed {industry} expertise within the area of drug discovery – ideally in molecular and/or RNA biology, together with an actual ardour for making use of scientific experience to drug discovery collaborations. Adept in working as a part of a multi-disciplinary crew, you have to to own the pliability required to work in a goal-oriented atmosphere, in addition to the next:Experience in creating, optimising and executing plate-based in vitro organic assays in a variety of transcriptional strategies, together with multiplex qRT-PCR, viewRNA, ISHExperience with laboratory automation and liquid dealing with utilized in drug discoveryExperience in troubleshooting organic assays to keep up knowledge high quality and supplyExperience at software of novel molecular biology strategies for drug discovery and goal validation, together with RNA/ribo-seq, CRISPR, CHiP, mutagenesis, cell line technology, artificial deadly screeningAbility to educate and mentor extra junior scientists – offering scientific enter to information experimental planning and knowledge interpretationAbility to steer an space of science or know-how in an effort to positively affect venture course and strategyConfidence in presenting your scientific work to colleagues and clientsAn capability to work to tight deadlines with robust organizational skillsAn capability to work in a secure method always guaranteeing adherence to procedures/SOPsA pro-active and optimistic downside fixing mind-set All candidates will need to have the best to work in th UK earlier than being thought-about. About DiscoveryDiscovery from Charles River is industry-proven within the profitable improvement of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors prior to now 17 years. Backed by greater than 650 scientists, our complete, built-in portfolio employs the newest know-how and platforms to supply chemistry, biology, and pharmacology providers that assist shoppers from the earliest levels of hit identification all over to IND. Our client-focused, collaborative strategy creates true partnerships that anticipate challenges, overcome obstacles, and transfer us ahead collectively on the journey of getting new medicine to market.About Charles RiverCharles River is an early-stage contract analysis group (CRO). We have constructed upon our basis of laboratory animal drugs and science to develop a various portfolio of discovery and security evaluation providers, each Good Laboratory Practice (GLP) and non-GLP, to assist shoppers from goal identification by preclinical improvement. Charles River additionally supplies a set of services and products to assist our shoppers’ medical laboratory testing wants and manufacturing actions. Utilizing this broad portfolio of services and products allows our shoppers to create a extra versatile drug improvement mannequin, which reduces their prices, enhances their productiveness and effectiveness to extend pace to market.With over 17,000 workers inside 90 services in 20 nations across the globe, we’re strategically positioned to coordinate worldwide assets and apply multidisciplinary views in resolving our shopper’s distinctive challenges. Our shopper base contains world pharmaceutical firms, biotechnology firms, authorities companies and hospitals and educational establishments all over the world. And in 2019, income elevated to $2.62 billion.At Charles River, we’re captivated with our function in bettering the standard of individuals’s lives. Our mission, our glorious science and our robust sense of goal information us in all that we do, and we strategy every day with the data that our work helps to enhance the well being and well-being of many throughout the globe. We have proudly supported the event of ~85% of the medicine accepted by the FDA in 2019.

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